Cancer Risk Prediction Test
Cancers have various causes, but some cancers are caused by genetic mutations of specific inherited genes. People who have such cancer-related mutations have far more risk of cancer than others. Hereditary cancers are caused by gene abnormalities inherited from parents, and the incidence of cancer in the same family is high. Thus, early detection and identification of the exact cause through gene diagnosis is required.
The most commonly known hereditary cancers are breast cancer, ovarian cancer, and colon cancer. For the incidence of breast cancer, 5%–10% is known to be genetically caused, and more than half of such cases are caused by abnormalities in genes called BRCA1 and BRCA2. When there is a mutation in the BRCA1 gene, the risk increases up to 87% after age 70 compared to when there is no variation. Moreover, various genes including MLH1 are found to be the main cause of colon/rectal cancer. With mutation, the incidence of cancer increases greatly.