Human


Macrogen delivers comprehensive access to human genomic variation through high-depth whole genome sequencing (WGS), powered by the latest-generation platforms offering ultra-long reads, exceptional accuracy, and uniform coverage across the genome.

Our WGS service is optimised for a wide range of applications — from cancer genomics and tumour/normal comparative studies (for detection of SNPs, CNVs, and structural variants) to population-scale genomics, pharmacogenomics, and analysis of inherited diseases, including rare and complex conditions. Both high- and low-depth options are available to suit your research goals.

With an annual capacity exceeding 500,000 whole genomes or equivalent, Macrogen is equipped to support projects of any size — from small pilot studies to large, multi-centre cohorts. Despite the complexity of large-scale sequencing, our standard turnaround time remains 4 to 6 weeks, ensuring efficient project delivery without compromising data quality.

Whole Genome Sequencing (WGS)

Platform Illumina Pacbio Oxford Nanopore
Novaseq X 150bpPE Revio PromethION
Sample type gDNA, Blood****, tissue****, FFPE****
Library kit type Truseq PCR free DNA kit

Truseq Nano DNA kit

HiFi Library ONT-LSK-114
Sample QC Requirement Total Amount: 100ng-2ug

DIN: >7.0

Volume: >20ul

Total Amount: 5.1ug

Average size: >30K

A260/280 ratio: 1>1.8

A230/280: >2.0

Volume: >20ul

Total Amount: 6.0ug

Average size: >30K

Turnaround time ** 2-4 weeks (express service) or 4-6 weeks (standard)
Date Analysis – illumina Re sequencing

– Isaac.v4 – Mapping, Variant Calling(SNP/Indel), CNV(Control-FREEC), SV(Manta)

– BWA-GATK.v4 – Mapping, Variant Calling(SNP/Indel), CNV(Control-FREEC), SV(Manta)

– Tumor-Normal Paired Analysis – SNP/Indel(Mutect2), CNV(Control-FREEC), SV(Manta)

Date Analysis – Pacbio

Re sequencing

– Mapping, Variant Calling(SNP/Indel), CNV, SV


Recommended Coverage / Reads lenghth 15X, 30X, 60X, 90X 5-10X 5-10X

* library construction platform

** TAT from sample QC passed

*** TAT 2-4 Express service

**** gDNA extraction fee applies

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